Stem Cell and Platelet Procedures for Injuries, Arthritis and Other Degenerative Conditions

We Are Bringing You the Future of Medicine, Today

Because of stem cells, the times are changing. This year is a kind of prologue in what I believe will be a monumental change in how orthopedic surgeons care for the musculoskeletal system. Until now, every scientific presentation in orthopedics, be it at a scientific meeting or in a scientific publication, ended with "more research is needed". Today that worn out phrase has been supplanted by "in the future, outcomes will be improved because of the use of stem cells." Outcomes scrutiny, evidenced based medicine, forms the foundation of how an orthopedic surgeon addresses a musculoskeletal condition.
Hindsight tells us much. By learning about regenerative medicine and stem cell management of orthopedic conditions, you are witnessing firsthand a paradigm shift in how to manage orthopedic conditions of the mature athlete. I acquired my initial knowledge through the educational process; then I introduced regenerative medicine and bone marrow concentrate into my orthopedic practice and now we are gathering outcomes data by integrating clinical stem cell practice with outcomes scrutiny.

This web site is not an effort to write a review about the scientific literature or the work of others. There is a paucity of scientific evidence to support much of what is done in the world of regenerative medicine. My objective is to reveal the future world of orthopedic care through my experiences and perceptions. I have put aside 38 years of what I know to be true in joint replacement. Accompany me in the new world of orthopedic stem cell care. - Mitchell Sheinkop, M.D.

  • About Mitchell Sheinkop - Orthopedic Surgeon and Professor Emeritus

    Mitchell B. Sheinkop, MD

    Dr. Mitchell SheinkopDr. Sheinkop is a Board-Certified Orthopedic Surgeon, former director of the joint replacement program and Professor Emeritus at Rush University Medical Center.

    He is a leading authority on the treatment of patients with complex hip and knee disorders, and is well known for his pioneering use of computer-assisted navigation, minimally-invasive technologies and hip resurfacing techniques. Dr. Sheinkop is a graduate of the Chicago Medical School and did fellowships in pediatric orthopedics and hand surgery. He has done extensive research in the fields of uni-compartmental, minimally invasive solutions, hip resurfacing systems, and navigated arthroplasty. Read Dr. Mitchell Sheinkop's complete bio
  • A Revolution in Biologics

    A Revolution in Biologics

    There is a major gap for orthopedic treatment options between conservative treatment and surgery. Platelet Rich Plasma and stem cells from Bone Marrow Concentrate offer a therapeutic treatment option.

    Platelet Rich Plasma / PRP

    Growth factors contained therein control cellular activity fundamental for repair. When I went to medical school, I was taught that the platelet function was solely to play a role in blood clotting. We now know that the function of platelets is more complex as they give rise to Growth Factors -Cytokines-in addition to partaking in the coagulation cascade.

    Stem Cell Treatments

    While there are multiple types of stem cells, in the present era of orthopedic care of the musculoskeletal system, the term stem cell should be understood to indicate an adult mesenchymal autologous source of origin. They come from your own bone marrow; not a fetus, not from someone else. Mesenchymal stem cells help repair muscle, bone cartilage and tendon. Since they are autologous, they are yours so no risk of genetic disease transmission. They act as construction managers helping other cells build and repair new musculoskeletal tissue. MSCs are used therapeutically because they recruited to sites of inflammation or tissue injury and secrete massive levels of bioactive substances that are both immune modulating and tropic ( build tissue). The potential tropic effect seems to diminish as we age; hence little chance of my influencing cartilage regrowth after age 50. However, the immunomodulation capacity of mesenchymal stem cells has a profound and immediate effect on joint chemistry and biology by muting or eliminating the chronic inflammation observed in osteoarthritis. As far as risks, the FDA allows use of these cells as long as they they are put back in the same patient and minimally manipulated.
  • An Exciting Update from a Recent Regenexx-SD Patient

    Dr. Sheinkop, Thank you so much for what you have done for me. I am on my 2nd week of getting back my life back and getting back into shape. I thought it would be a good idea to give you an update on my condition.
    • Day of procedure:Slight tenderness in lower back. Used crutches for what ever movement was absolutely necessary. Stayed off my feet all day. When I went to bed I noticed a reduction in pain. I could lay on my back and not use a pillow under my knee for comfort.
    • Day 2: 100% pain free! What is going on inside of my knee and hip? Over a year on pain killers. The last few months as many as 12 hydrocodone pills to make it through an active day and still have a lot of pain. All has changed overnight. Very limited activity and still on crutches. Tenderness in lower back is gone. Never experienced the expected backache.
    • Day 3 and 4: Still pain free and using crutches.
    • Day 5 Sunday: I am done but with the crutches. I still have a noticeable limp but from habit and not pain.Took a 15 minute walk. This is the longest walk I have taken in a very long time. First noticed muscle pain in the left hip, not the right that I had the procedure on. This pain was from finally working the muscle. The right hip gave me a little pain when I was feeling bold and took a bigger stride. At the end of the day I noticed slight discomfort from the activity. Could not say this was actually pain.
    • Day 6: Went to work for 2 hours. Still had some discomfort so I skipped the walk today.
    • Day 7: Stayed home from work today. No discomfort today so I took 15 minute walk. Same discomfort at end of day.
    • Day 8, 9 and 10: Same activity as Day 7 with discomfort at end of day.
    • Plan to try biking on day 11 at Rock Valley College. There is a nice flat bike path there.
    Biggest problem was the migraine I had starting day one lasting through Sunday. I did not take anything for the pain. I had Imitrex here for this but did not want to take the chance. Stopping hydrocodone cold turkey was a challenge. Sleepless nights, skin crawling and high anxiety every night. Not as bad last night. Maybe I am turning the corner. A lot of late night hot showers and ice cream helps a little. I have not taken any medications of any kind since July 31. No alcohol since July 4th. Thank you very much for allowing me to be part of this study. This is truly a miracle. Much thanks to your team and staff. Always friendly, informative and more than willing to take the extra time to explain the details. T.K.